How does ALS kill you?

Amyotrophic lateral sclerosis (ALS) primarily leads to death by causing progressive degeneration of motor neurons in the brain and spinal cord. This results in muscle weakness and atrophy, affecting the ability to breathe, swallow, and perform basic bodily functions. As respiratory muscles weaken, individuals may experience respiratory failure, which is often the leading cause of death in ALS patients. While cognitive functions may remain intact, the loss of motor control severely impacts quality of life and can ultimately be fatal.