Why are sex linked conditions more common in men than in women?

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2026-05-16 09:35

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Sex-linked conditions, particularly those linked to the X chromosome, are more common in men because they have only one X chromosome (XY), while women have two (XX). If a man inherits a recessive allele for a condition on his single X chromosome, he will express that condition. In contrast, a woman would need to inherit two copies of the recessive allele (one from each X chromosome) to express the condition, making it less likely for women to be affected. Thus, the single X chromosome in men increases their susceptibility to X-linked disorders.

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