Is it normal to feel worse after taking pristiq after one day?

It's not uncommon to experience side effects when starting a new antidepressant like Pristiq (desvenlafaxine), especially in the initial days of treatment. Some individuals may feel worse before they start to feel better as their body adjusts to the medication. However, if side effects are severe or persist, it's important to consult your healthcare provider for guidance. They can assess your situation and determine the best course of action.