There may be a slight difference in the time it takes to get into your system. I have heard people say that the liquid worse for your teeth and tongue but it's probably minimal at best. Methadone 10mg pills take an hour and Ten minutes to feel the effect. With the liquid it usually takes around 25 minutes to a half an hour. Also Liquid is injectable where as some forms of the pills will gell up on you making them not injectable. Another problem is that the pills have been known to cause more nausea.
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