George McClellan...replaced by...
John Pope...after Second Manassas, replaced by..
George McClellan...after Antietam, replaced by...
Ambrose Burnside..after Fredericksberg, replaced by...
Joe Hooker..after Chancellorsville, replaced by...
George Meade...Meade held the title through the war but Grant was really in charge during the Overland Campaign.
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