What is wrong when hands are painful to make a fist?

Pain in the hands when making a fist can indicate several issues, such as Arthritis, tendinitis, or ligament injuries. Conditions like carpal tunnel syndrome or repetitive strain injuries can also contribute to discomfort. Inflammation or damage to the joints, tendons, or muscles can lead to pain and reduced range of motion. It's advisable to consult a healthcare professional for an accurate diagnosis and appropriate treatment.