To give mouth-to-mask breaths during CPR, first ensure the scene is safe, then position the victim supine on a firm surface. Open the airway using the head-tilt, chin-lift maneuver, and place the mask over the victim's mouth and nose, ensuring a good seal. Pinch the victim's nose, give two breaths lasting about 1 second each, watching for chest rise. Continue with chest compressions, alternating with breaths as needed, typically at a ratio of 30 compressions to 2 breaths.
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