A base runner runs into a player with the ball is he out?

yes unless he is standing on the base

It is also interference.

Y-THINK-Y

These answers assume we are talking about a batted ball (not clear from the question). A runner hit by a ball thrown by a fielder is not out, unless his interference with the throw was intentional.

It is NOT interference if the ball first passes a fielder other than the pitcher. EXAMPLE: If the runner were to be running behind the fielder, and the ball went through the fielder's legs and hit the runner, the ball is live and there is no interference.

A runner hit by a fair batted ball while standing on the base is out.