What will humans look like 1000 years from now?

Most likely, we won't change much. Evolution takes place slowly so that in order to see any sort of difference you would need at least a few hundred thousand to a few million years. So, 1000 years is merely a blink of an eye in evolutionary terms.

Answer

People will probably have developed skin better equipped for the hole in the ozone layer. Maybe we will be living underwater... or on the moon or mars! But what is for sure, we will probably be different because the world is Constantly changing and so must we to adapt to the surroundings... do you get my drift???