How from padre island to Oklahoma City?

To travel from Padre Island to Oklahoma City, you can take U.S. Highway 77 north from Padre Island, then merge onto I-37 North towards San Antonio. From San Antonio, take I-35 North, which will lead you through various cities in Texas until you reach the Oklahoma border. Continue on I-35 North until you arrive in Oklahoma City. The drive typically takes around 8-10 hours, depending on traffic and road conditions.