What is the difference between aspartame and saccharin?

Aspartame and saccharin are both artificial sweeteners used as sugar substitutes, but they differ in their chemical structure and sweetness levels. Aspartame is made from two amino acids, aspartic acid and phenylalanine, and is approximately 200 times sweeter than sugar, but it breaks down at high temperatures, making it unsuitable for baking. Saccharin, on the other hand, is a sulfonamide compound that is around 300 to 400 times sweeter than sugar and is more stable under heat, making it often used in cooking and baking. Additionally, while both have been subject to safety evaluations, saccharin was once linked to health concerns but is now considered safe for consumption by regulatory agencies.