How could it have been different for the European settlers if there had been no native Americans to meet with them when they came to this continent?

If there had been no Native Americans when European settlers arrived, the settlers might have faced greater challenges in adapting to the unfamiliar environment, as they would not have had access to Indigenous knowledge about local agriculture, hunting, and survival techniques. The absence of established trade networks and existing agricultural systems could have led to higher mortality rates due to starvation and disease. Additionally, the lack of indigenous populations could have altered the settlers' motivations and justifications for colonization, potentially leading to different territorial claims and interactions with other European powers. Overall, their experience in the New World would likely have been more difficult and less sustainable.