A stuffed 13-pound turkey should be cooked for about 3 to 3.5 hours in a preheated oven at 325°F (165°C). It's important to ensure the internal temperature of both the turkey and the stuffing reaches 165°F (74°C) for safe consumption. To check doneness, use a meat thermometer in the thickest part of the thigh and the center of the stuffing. Let the turkey rest for at least 20 minutes before carving.
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