Transcription begins when RNA polymerase, aided by sigma (σ) factors, binds to specific DNA sequences known as promoters. The σ factor helps the polymerase recognize and attach to the promoter region, facilitating the unwinding of the DNA to initiate RNA synthesis. As transcription progresses, RNA polymerase elongates the RNA transcript until it encounters a terminator sequence, which signals the end of transcription and causes the polymerase to disengage, releasing the newly synthesized RNA molecule. This process ensures that genes are accurately transcribed into RNA, which can then be translated into proteins.
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