Disagreements involving slavery and states' rights were two of the main causes of?

Disagreements involving slavery and states' rights were two of the main causes of the American Civil War. The Southern states advocated for the right to maintain slavery as an essential part of their economy and culture, while Northern states sought to limit its expansion. The conflict over states' rights intensified as Southern states believed they should have the authority to govern themselves, including making decisions about slavery. This fundamental clash ultimately led to secession and the outbreak of war in 1861.