What are the differences between selective and nonselective NSAIDs and how do they impact their effectiveness in treating pain and inflammation?

Selective NSAIDs target specific enzymes in the body that are involved in inflammation, while nonselective NSAIDs inhibit multiple enzymes. Selective NSAIDs may be more effective in treating pain and inflammation with potentially fewer side effects, as they target specific pathways. Nonselective NSAIDs may have a broader impact on the body, leading to a higher risk of side effects such as gastrointestinal issues.