Research shows that neurofibrillary tangles associated with the disintegration of microtubules are the primary cause of Alzheimer's disease. If microtubules disintegrate what then might happen to brai?

If microtubules disintegrate, it disrupts the transport system within neurons, impairing the delivery of essential nutrients and signaling molecules. This can lead to neuronal dysfunction and ultimately cell death, contributing to cognitive decline and the hallmark symptoms of Alzheimer’s disease. Additionally, the accumulation of neurofibrillary tangles can exacerbate inflammation and further damage surrounding brain tissue. Overall, the integrity of microtubules is crucial for maintaining healthy brain function.