Is a 7.3 E4od interchangeable with a 460?

No, a 7.3 E4OD transmission is not directly interchangeable with a 460 engine. The E4OD is designed for use with Ford's 7.3L diesel engines, while the 460 is a gas engine that typically uses a different transmission, such as the C6 or C6-based models. Additionally, the mounting points, bellhousing designs, and electronics differ, making direct swaps impractical without significant modifications.