Is there a train service between Detroit and Chicago?

Yes, there is. There are three trains a day that travel between Detroit and Chicago each way.

The trains from Detroit leave at 7:23 am, 11:46 am and 5:53 pm.

The trains from Chicago leave at 8:30 am, 12:15 pm and 6:00 pm.

The journey takes between 5 1/2 and 6 hours each way.