What does UGT mean?

UGT stands for "Uridine Diphosphate Glucuronosyltransferase," which is a family of enzymes involved in the process of glucuronidation, a key detoxification pathway in the liver. These enzymes catalyze the conjugation of glucuronic acid to various substrates, including drugs and endogenous compounds, facilitating their excretion from the body. Variations in UGT genes can influence individual responses to medications and susceptibility to certain diseases.