Who discovered biotin?

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1127297

2026-06-01 04:55

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W. G. Bateman discovered biotin in 1916. That adding raw eggwhite to an otherwise adequate diet produced toxicity and disease. Called egg-white injury, the symptoms includedeffects on the skin (scaly dermatitis and hair loss), thenervous system (depression, lassitude, and muscle pain),the gastrointestinal tract (anorexia and nausea), and even the cardiovascular system (abnormal heart action, i.e.,changes in the electrocardiogram). Later research identified the culprit to be avidin, a protein in egg white which avidly binds biotin, preventing its absorption. Thus, the biological necessity of biotin became evident, and by 1935scientists had isolated it in pure form. Biotin, originally calledvitamin H after the German Word Haut meaning "skin", belongs to the water soluble B vitamin class.

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