How do you calculate coefficient of inbreeding?

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1101816

2026-05-20 22:05

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The coefficient of inbreeding (F) can be calculated using several methods, with one common approach being the pedigree method. This involves identifying all the common ancestors in an individual's ancestry and determining their contributions to the individual's genotype. The formula used is F = Σ (1/2)^n, where n represents the number of generations back to the common ancestor. Alternatively, F can also be calculated using the Wright's inbreeding coefficient formula, which accounts for the probability of inheriting identical by descent alleles from both parents.

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