What does epiphyseal closure mean?

Epiphyseal closure refers to the process in which the growth plates, or epiphyseal plates, in long bones fuse, marking the end of longitudinal bone growth. This usually occurs after puberty when hormonal changes lead to the ossification of these cartilage areas. Once closure happens, bones can no longer grow in length, signifying that an individual has reached their final adult height. The timing of epiphyseal closure varies by individual and is influenced by factors such as genetics and sex.