Can a 6 year old golden retriever female have pups with a 1 year old male?

Yes, a 6-year-old female golden retriever can have puppies with a 1-year-old male, provided she is in good health and has no reproductive issues. Female dogs generally remain fertile until about 8 years of age, though fertility may decrease as they age. It's important to ensure that both dogs are healthy, up-to-date on vaccinations, and screened for any genetic issues before breeding. Consulting a veterinarian for guidance is recommended.