Will Vyvanse show up on DOT's CDL drug test?

Yes, Vyvanse (lisdexamfetamine) can show up on the Department of Transportation's (DOT) CDL drug test, as it is an amphetamine. DOT drug screenings typically test for amphetamines, and since Vyvanse is related to this class of drugs, it may lead to a positive result. However, if you have a valid prescription for Vyvanse, it’s important to inform the testing agency and your employer to avoid any issues with compliance.