The inhibition of FSH (follicle-stimulating hormone) primarily occurs through negative feedback mechanisms involving sex hormones. In females, elevated levels of estrogen and inhibin produced by developing follicles suppress FSH release from the pituitary gland. In males, testosterone and inhibin produced by Sertoli cells in the testes exert a similar inhibitory effect on FSH secretion. This regulation helps maintain hormonal balance and proper reproductive function.
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