The Columbian Exchange led to significant unintended consequences, including the spread of diseases like smallpox, which devastated Indigenous populations in the Americas, resulting in massive demographic shifts. Additionally, the introduction of new crops and livestock transformed agricultural practices and diets on both sides of the Atlantic, but also contributed to environmental changes and the displacement of local species. The exchange fostered economic systems based on exploitation and colonization, laying the groundwork for social and racial hierarchies that persist today.
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