To reprogram the remote key for a Mercedes-Benz ML 350, first, ensure you have all keys available, as the process will erase old keys. Insert the key into the ignition and turn it to the "On" position without starting the engine. Then, press the "Lock" button on the remote for several seconds until you hear a confirmation sound from the vehicle. Finally, turn the key back to the "Off" position and remove it; the remote should now be reprogrammed.
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