I'm not sure what you mean by interchangeable, but if you mean can you take one laptop hard drive and put into another the answer would most likely be yes. Assuming they are both based upon the same board communication function. You can't interchange a sata HD with IDE. If they are both Sata or IDE then there is no problem. You can probably tell if they are sata or ide by going into the computers biOS. (Settings function before your computer boots.) You can also purchase an adapter that will allow you to hook up your laptop hard drive to your desktop. Hope this helps -Brent
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