MS-DOS (Microsoft Disk Operating System) is an operating system that was widely used in the 1980s and early 1990s, primarily for managing files and running applications on personal computers. In contrast, exFAT (Extended File Allocation Table) is a file system designed by Microsoft for flash drives and external storage devices, allowing for large file sizes and greater compatibility across different operating systems. While MS-DOS refers to an operating system, exFAT is a method of organizing and storing data on storage media.
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