Do you have to take anti-estrogen with androdrol?

No you do not. Androdrol already contains a moderate amount, however It you are prone to gyno you might want to follow up with an e blocker and definitely a PCT after you end your cycle(no more than 8 week cycle, recommend 6). I have used this product hoping it would compare to Omnevol. It does work, but is not as good. Expect approx 8-15 lbs in 6 weeks average. This depends on your diet and how much dedication, experience, and motivation you have!