Should you take your clothes off in sex?

There is no other physical way to perform sexual intercourse with clothes on, so the answer to your question is: Yes, clothes should be removed by both parties (you and the other person).

It's hard to refute the clear and direct thinking of the above answer. I would suggest though that when it appears that sexual activity is a possibility, the last thing you want to do is to follow a check list: "OK, at this time clothing should be removed". Wordlessly and creatively negotiating the obstacles presented by clothing is definitely part of the fun.