How would positive pressure ventilation affect measured fio2?

Positive pressure ventilation can significantly affect the measured fraction of inspired oxygen (FiO2) by delivering a higher concentration of oxygen directly to the patient's lungs. This method allows for precise control over the FiO2, which can be adjusted according to the patient's needs. However, if the ventilator settings are not properly calibrated or if there is a leak in the system, the actual FiO2 delivered may differ from the intended value. Therefore, close monitoring is essential to ensure that the patient receives the appropriate oxygen levels.