How many US companies have more than 100 employees?

As of recent estimates, there are approximately 20,000 to 25,000 companies in the United States that have more than 100 employees. This number can vary based on economic conditions and changes in business dynamics. The majority of these companies are concentrated in sectors such as healthcare, manufacturing, and retail. For the most accurate and current figures, consulting resources like the U.S. Census Bureau or business databases would be advisable.