It depends on the tolerance of the patient to opiates, but generally that dosage lasts between 4-6 hours before you start feeling it wear off and having the pain come back.. What you're describing is the generic version of Percocet.
Since that dose is using the lowest Tylenol component (325mg) you can boost the effectiveness by taking additional Tylenol with it. Don't exceed 750mg per dose, combining the drug and the extra Tylenol.
One mistake many people make is to wait until the dose wears off or to see how long they can go without taking it because they're afraid of becoming dependent. That's old thinking, and stupid to boot because you're only hurting yourself. It took me a very long time to get away from that kind of thinking.
Research has since determined that if a patient takes the prescribed dose on time as directed when directed and not PRN (as needed), the patient actually feels better, gets more relief, and winds up using less medication. I've found that to be the truth as I've been in pain management and an opiate patient for 10 years.
Copyright © 2026 eLLeNow.com All Rights Reserved.
