Triamterene and hydrochlorothiazide (HCTZ) typically stay in the body for a relatively short period. Triamterene has a half-life of about 3 to 14 hours, while HCTZ has a half-life of 6 to 15 hours. It usually takes about 5 to 6 half-lives for a drug to be eliminated from the body, so you can expect both components to be cleared within approximately 1 to 3 days after the last dose. However, the exact duration can vary based on individual factors like metabolism and kidney function.
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