What is the significance of Marbury v Madison and Brown v Board of Education of Topeka Kansas?

Marbury v. Madison confirmed the fact that courts have the power of judicial review.

In Brown v. Board of Education, the Supreme Court used this power to declare all laws permitting segregation in the school system in Kansas unconstitutional because they violated the equal protection clause of the Constitution.

The significance of the two cases together is that in Marbury the Supreme Court confirmed that the power existed and in Brown the Supreme Court used it to declare segregation laws unconstitutional.