What does the statement no person held to service for labor in one state under the laws thereof escaping to another shall consequence of any law or regulation there in be discharged from such service?

The statement refers to a provision in the U.S. Constitution, specifically the Fugitive Slave Clause (Article IV, Section 2). It asserts that individuals who were enslaved and escaped from one state to another must be returned to their owners and cannot be freed by the laws of the state they fled to. This clause was a legal foundation for the enforcement of slavery and contributed to the tensions leading up to the Civil War. It reflects the complexities of state versus federal authority regarding the institution of slavery in the United States.