Can you shoot a deer with a 410?

Yes, but only at close range - 20 yards max. The shot in shotgun shells is the same size no matter the caliber - 410,20 12 ga- 7, 7.5, or 8 is best for dove.the larger the guage , the more pellets per shell. In no wind condition, 410, 20 12 16 ga all work fine, but your range is limited a lot with a 410. but they will bring em down. I've shot one for years, and they're better suited for squirrel, rabbit, or other small varmints at close range.