What major advantage of the transmission electron microscope have over a compound light microscope what is the major disadvantage?

The major advantage of a transmission electron microscope (TEM) over a compound light microscope is its ability to achieve much higher resolution, allowing for visualization of cellular structures at the nanometer scale. This is due to the use of electrons instead of light, which have shorter wavelengths. However, the major disadvantage of TEM is that it requires extensive sample preparation, often resulting in the destruction of the specimen, and it cannot be used to observe live samples.