Who has less dehydrogenase enzymes and take longer to eliminate alcohol from the system?

Individuals with lower levels of dehydrogenase enzymes, particularly alcohol dehydrogenase, tend to take longer to eliminate alcohol from their systems. This is often observed in women, who generally have lower enzyme activity compared to men, leading to slower alcohol metabolism. Additionally, genetic variations can also affect enzyme levels, resulting in some individuals metabolizing alcohol more slowly. As a result, these factors can increase the risk of alcohol-related effects and toxicity.