Several key events led to the outbreak of the Civil War in the United States. The 1850 Compromise attempted to balance slave and free states but ultimately failed, exacerbating tensions. The publication of Harriet Beecher Stowe's "Uncle Tom's Cabin" in 1852 stirred anti-slavery sentiments, while the Dred Scott decision in 1857 denied citizenship to African Americans and invalidated the Missouri Compromise. The election of Abraham Lincoln in 1860, viewed as a threat to slavery, prompted Southern states to secede, igniting the conflict.
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