245 miles taking this route:
- Take I-55 NORTH to U.S. 278 EAST to OXFORD at EXIT 243A.
- Take U.S. 278 EAST to U.S. 45 in Tupelo. Follow signs to U.S. 45 NORTH.
- Take U.S. 45 NORTH to U.S. 78. EXIT off onto U.S. 78 EAST to BIRMINGHAM.
- Take U.S. 78 (FUTURE I-22 CORRIDOR) EAST to Fulton. The exit for Fulton is EXIT 104 [SR-25 NORTH (S Adams St)].
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