When depression symptoms are major or severe what is likely to appear?

When depression symptoms are major or severe, individuals may experience debilitating changes in mood, energy, and motivation. Common manifestations include persistent sadness, hopelessness, loss of interest in previously enjoyed activities, and significant difficulty in functioning in daily life. Physical symptoms like fatigue, changes in appetite, and sleep disturbances may also be prominent. In extreme cases, thoughts of self-harm or suicide can arise, necessitating immediate professional intervention.