The varicella-zoster virus (VZV), which causes chickenpox and shingles, is primarily targeted by IgM antibodies during the initial immune response to an acute infection. IgM antibodies are produced shortly after the onset of infection and indicate recent exposure to the virus. Their presence can be used to help diagnose active varicella or shingles. However, IgG antibodies are typically measured to indicate past infection or immunity.
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