Do you need a cdl to drive a freightliner business class truck?

Depends on the exact model. Freightliner Business Class trucks range from Class 5 to Class 8. Class 7 and 8 require a CDL. Classes 5 and 6 only require one if they're either transporting hazardous materials in a quantity requiring placards or if they're buses designed to transport more than 15 persons (including the driver).