What do prohibition goes beyond the bounds of reason in that it attempts to control a mans appetite by legislation and makes a crime out of things that are not crimes mean?

This statement suggests that prohibition, by attempting to regulate personal behaviors and desires through laws, oversteps rational governance. It implies that legislating against certain appetites, like alcohol consumption, criminalizes actions that are natural and not inherently harmful. This approach can be seen as an infringement on individual freedoms, as it seeks to impose moral standards through legal means rather than encouraging personal responsibility. Ultimately, it argues that such attempts at control are misguided and counterproductive.