When would the quote no man is an island be used today?

It comes from John Donne. It refers to the human condition, we as humans need interaction with others. Trying to live alone, without association with other people is debilitating and self defeating. Whether we like others is not the point, we cannot do without them. It applies today as much as it ever did, in fact in the modern society even more so. I think this site exemplifies it for me: There is much I do not know, but if I need to get an answer somewhere then can always message any number of folk here & communicate with them, that in itself shows that we, the internet community, are not isolated.