How do you reply to ise kala?

The phrase "ise kala" is often used in some cultures to express a sense of disbelief or surprise, similar to saying "are you serious?" in English. A suitable reply could be to clarify your statement or provide more context to address the disbelief. You might say something like, "Yes, I really mean it" or "Let me explain what I meant." This helps to engage in a conversation and clear up any confusion.