When a cell is at rest it has a membrane potential that is?

When a cell is at rest, it has a membrane potential that is typically negative, often around -70 millivolts (mV). This resting membrane potential is primarily established by the differential distribution of ions, particularly sodium (Na+) and potassium (K+), across the cell membrane, maintained by ion channels and the sodium-potassium pump. The inside of the cell is more negatively charged compared to the outside, creating an electrochemical gradient that is crucial for the generation of action potentials and cellular signaling.